⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545704 | 0.86 | DHFR (0.33) | — | |
| SCHEMBL30372989 | 0.79 | GMNN (0.30) | — | |
| SCHEMBL28185880 | 0.79 | — | — | |
| SCHEMBL17767287 | 0.76 | MGLL (0.42) | — | |
| SCHEMBL13837373 | 0.74 | MGLL (0.46) | — | |
| SCHEMBL23505876 | 0.70 | GMNN (0.30) | — | |
| SCHEMBL13698594 | 0.70 | GMNN (0.30) | — | |
| SCHEMBL8465143 | 0.70 | — | — | |
| SCHEMBL762384 | 0.69 | — | — | |
| SCHEMBL28675006 | 0.69 | F2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114605226-A | Method for continuously synthesizing 1,1,1, 3-tetrachloropropane | 中国科学院上海有机化学研究所 | 2022-06-10 | — | — | CN | claimed |
| CN-114605225-A | Method for continuously synthesizing 1,1,1,3, 3-pentachloropropane | 中国科学院上海有机化学研究所 | 2022-06-10 | — | — | CN | claimed |
| CN-111267439-A | Plate, preparation method of plate and use method of plate | 十倍好智能家居(广州)有限公司 | 2020-06-12 | — | — | CN | claimed |
| CN-107099201-B | Water-dilutable polyvinyl fluoride paint and coating and forming method thereof | 广科工业股份有限公司 | 2020-02-07 | — | — | CN | claimed |
| CN-105732624-B | The preparation method and its usage of pyrroles [4,3,2-de] quinoline -2 (1H) -one class BRD4 protein inhibitor | 中国药科大学 | 2019-08-02 | — | — | CN | claimed |
| CN-105732624-A | Preparation method and application of pyrrole [4,3,2-de] quinoline-2-(1H)-ketone BRD4 protein inhibitor | 中国药科大学 | 2016-07-06 | — | — | CN | claimed |
| CN-114605225-A | Method for continuously synthesizing 1,1,1,3, 3-pentachloropropane | 中国科学院上海有机化学研究所 | 2022-06-10 | — | — | CN | disclosed |
| CN-114605226-A | Method for continuously synthesizing 1,1,1, 3-tetrachloropropane | 中国科学院上海有机化学研究所 | 2022-06-10 | — | — | CN | disclosed |
| CN-111267439-A | Plate, preparation method of plate and use method of plate | 十倍好智能家居(广州)有限公司 | 2020-06-12 | — | — | CN | disclosed |
| CN-108340676-B | Cleaning liquid, cleaning method and apparatus, ink jet recording method and apparatus | 株式会社理光 | 2020-05-01 | — | — | CN | disclosed |
| CN-105732624-B | The preparation method and its usage of pyrroles [4,3,2-de] quinoline -2 (1H) -one class BRD4 protein inhibitor | 中国药科大学 | 2019-08-02 | — | — | CN | disclosed |
| CN-108409592-A | A kind of impurity and its synthetic method of Levetiracetam | 浙江华海药业股份有限公司 | 2018-08-17 | — | — | CN | disclosed |
| CN-105732624-A | Preparation method and application of pyrrole [4,3,2-de] quinoline-2-(1H)-ketone BRD4 protein inhibitor | 中国药科大学 | 2016-07-06 | — | — | CN | disclosed |
| US-8716314-B2 | Isotopologues of thalidomide | CELGENE CORPORATION (US) | 2014-05-06 | — | — | US | disclosed |
| US-8309537-B2 | Compositions and methods for treating colitis | AERPIO THERAPEUTICS INC. (US) | 2012-11-13 | — | — | US | disclosed |
| US-20110112055-A1 | COMPOSITIONS AND METHODS FOR TREATING COLITIS | AERPIO THERAPEUTICS LLC | 2011-05-12 | — | — | US | disclosed |
| US-20110110961-A1 | PROLYL HYDROXYLASE INHIBITORS | AERPIO THERAPEUTICS LLC | 2011-05-12 | — | — | US | disclosed |
| US-20110111058-A1 | METHODS FOR INCREASING THE STABILIZATION OF HYPOXIA INDUCIBLE FACTOR-1 ALPHA | AERPIO THERAPEUTICS LLC | 2011-05-12 | — | — | US | disclosed |
| CN-101160322-A | Molecules and chimeric molecules thereof | APOLLO LIFE SCIENCES LTD (AU) | 2008-04-09 | — | — | CN | disclosed |
| CN-1074933-C | Anti-stress, anti-impairment and anti-aging drug and process for manufacturing thereof | RIGA D (RO) | 2001-11-21 | — | — | CN | disclosed |