Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 10/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20799444 | 0.79 | CYP4F2 (0.39) | CYP4F2CYP4A11FYNEGLN1NPC1 | |
| SCHEMBL17954247 | 0.76 | TSHR (0.36) | CYP4F2CYP4A11FYNEGLN1NPC1 | |
| SCHEMBL17954214 | 0.73 | CYP4F2 (0.53) | CYP4F2CYP4A11FYNNPC1RAB9A | |
| SCHEMBL6667804 | 0.68 | MRGPRX4 (0.51) | CYP4F2CYP4A11NPC1RAB9AMAPT | |
| SCHEMBL12951814 | 0.68 | TDP1 (0.48) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29442637 | 0.68 | TDP1 (0.48) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16624624 | 0.68 | CYP4F2 (0.42) | CYP4F2CYP4A11NPC1RAB9AMAPT | |
| SCHEMBL17954210 | 0.68 | CYP4F2 (0.49) | CYP4F2CYP4A11FYNNPC1RAB9A | |
| SCHEMBL18165308 | 0.67 | FFAR1 (0.60) | CYP4F2CYP4A11 | |
| SCHEMBL8019903 | 0.65 | CASP3 (0.64) | FYNNPC1RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052107-B1 | ORGANIC COMPOUNDS TO TREAT HEPATITIS B VIRUS | NOVARTIS AG (CH) | 2018-05-02 | — | — | EP | disclosed |