⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27396948 | 0.92 | — | — | |
| SCHEMBL20386572 | 0.83 | — | — | |
| SCHEMBL20808560 | 0.83 | FBP1 (0.33) | — | |
| SCHEMBL25797616 | 0.82 | — | — | |
| SCHEMBL22112164 | 0.81 | FBP1 (0.47) | — | |
| SCHEMBL24145917 | 0.78 | FBP1 (0.33) | — | |
| SCHEMBL10034881 | 0.75 | — | — | |
| SCHEMBL24497709 | 0.73 | EPHX1 (0.30) | — | |
| SCHEMBL22223541 | 0.73 | FBP1 (0.30) | — | |
| SCHEMBL18874536 | 0.73 | FBP1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3736334-A1 | RNAI COMPOSITIONS TO TREAT APOC3-RELATED DISEASES | Arrowhead Pharmaceuticals, Inc. (US) | 2020-11-11 | — | — | EP | disclosed |
| EP-3052107-B1 | ORGANIC COMPOUNDS TO TREAT HEPATITIS B VIRUS | NOVARTIS AG (CH) | 2018-05-02 | — | — | EP | disclosed |