Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | AMDHD2 | Q9Y303 | 1/20 | 0.38 |
| ▸ | PGD | P52209 | 1/20 | 0.38 |
| ▸ | IGF2R | P11717 | 4/20 | 0.35 |
| ▸ | ADSS2 | P30520 | 1/20 | 0.33 |
| ▸ | TK1 | P04183 | 3/20 | 0.32 |
| ▸ | UMPS | P11172 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24145917 | 0.86 | FBP1 (0.33) | FBP1PGD | |
| SCHEMBL20808560 | 0.85 | FBP1 (0.33) | FBP1PGD | |
| SCHEMBL25797616 | 0.84 | — | — | |
| SCHEMBL22223541 | 0.81 | FBP1 (0.30) | FBP1 | |
| SCHEMBL18874536 | 0.81 | FBP1 (0.30) | FBP1 | |
| SCHEMBL20101356 | 0.81 | — | — | |
| SCHEMBL20673343 | 0.80 | FBP1 (0.53) | FBP1AMDHD2PGDIGF2RADSS2 | |
| SCHEMBL16710626 | 0.80 | FBP1 (0.53) | FBP1AMDHD2PGDIGF2RADSS2 | |
| SCHEMBL20386572 | 0.78 | — | — | |
| SCHEMBL14157994 | 0.77 | FBP1 (0.55) | FBP1AMDHD2PGDIGF2RADSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200190515-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2020-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200190515-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | RNASE1, RNASEH1, RNASEL | FBP1 908/4885AMDHD2 372/4885PGD 1566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.