Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | PTGIR | P43119 | 10/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 6/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | FPR1 | P21462 | 2/20 | 0.31 |
| ▸ | FPR2 | P25090 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16624654 | 0.85 | TDP1 (0.39) | TDP1NPC1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL21610293 | 0.73 | TDP1 (0.43) | TDP1NPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL16624730 | 0.72 | SMN1; SMN2 (0.48) | TDP1NPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL20799451 | 0.66 | HPGD (0.46) | TDP1ALDH1A1 | |
| SCHEMBL20026779 | 0.66 | KMT2A (0.41) | SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL20306216 | 0.66 | KMT2A (0.41) | SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL17954336 | 0.65 | HPGD (0.44) | TDP1ALDH1A1 | |
| SCHEMBL22333840 | 0.65 | DHFR (0.46) | TDP1NPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL10068094 | 0.65 | CHRM2 (0.33) | ALDH1A1 | |
| SCHEMBL18538124 | 0.64 | BRD4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052107-B1 | ORGANIC COMPOUNDS TO TREAT HEPATITIS B VIRUS | NOVARTIS AG (CH) | 2018-05-02 | — | — | EP | disclosed |