Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31585114 | 0.82 | ALDH1A1 (0.38) | ALDH1A1GAAHTTALOX12HIF1A | |
| SCHEMBL840544 | 0.82 | ALDH1A1 (0.52) | ALDH1A1GAAHTTALOX12HIF1A | |
| Hydrochloric Acid SCHEMBL6981827 | 0.80 | GAA (0.50) | ALDH1A1GAAHTTALOX12HIF1A | |
| SCHEMBL31554197 | 0.79 | GAA (0.37) | ALDH1A1GAAHTTALOX12HIF1A | |
| SCHEMBL741007 | 0.78 | ALDH1A1 (0.64) | ALDH1A1GAAHTTALOX12HIF1A | |
| SCHEMBL29549360 | 0.78 | ALDH1A1 (0.64) | ALDH1A1GAAHTTALOX12HIF1A | |
| SCHEMBL6895537 | 0.78 | LMNA (0.44) | ALDH1A1GAAHTTALOX12HIF1A | |
| SCHEMBL29661836 | 0.78 | LMNA (0.44) | ALDH1A1GAAHTTALOX12HIF1A | |
| SCHEMBL512377 | 0.74 | ALDH1A1 (0.59) | ALDH1A1GAAHTTALOX12HIF1A | |
| SCHEMBL2244195 | 0.74 | ALDH1A1 (0.59) | ALDH1A1GAAHTTALOX12HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081672-A1 | BIARYL LIGANDS FOR TRANSITION METAL-CATALYZED REACTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-05-03 | — | — | WO | disclosed |
| US-20180117574-A1 | BIARYL LIGANDS FOR TRANSITION METAL-CATALYZED REACTIONS | UNIV CALIFORNIA (US) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180117574-A1 | BIARYL LIGANDS FOR TRANSITION METAL-CATALYZED REACTIONS | EPHA2, L1CAM, ERBB2 | ALDH1A1 801/4885GAA 2633/4885HTT 4829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.