Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 11/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL92349 | 0.83 | RIPK1 (0.31) | CA2CA1 | |
| SCHEMBL12027013 | 0.82 | ELANE (0.45) | ELANEMAPTKMT2ATSHR | |
| SCHEMBL6124939 | 0.79 | POLB (0.34) | MAPTCA2ALDH1A1CA1 | |
| SCHEMBL22909596 | 0.78 | ELANE (0.35) | ELANE | |
| SCHEMBL27435323 | 0.78 | — | — | |
| SCHEMBL14249207 | 0.77 | POLB (0.33) | MAPTCA2ALDH1A1CA1 | |
| SCHEMBL22970148 | 0.77 | F2 (0.38) | CA2CA1 | |
| SCHEMBL13713615 | 0.77 | F2 (0.34) | CA2CA1 | |
| SCHEMBL12793115 | 0.76 | ELANE (0.41) | ELANE | |
| SCHEMBL19335424 | 0.76 | ELANE (0.41) | ELANEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10815379-B2 | pH sensitive fluorescent probe | THE UNIVERSITY OF TOKYO (JP) | 2020-10-27 | — | — | US | disclosed |
| US-20180118943-A1 | PH SENSITIVE FLUORESCENT PROBE | THE UNIVERSITY OF TOKYO (JP) | 2018-05-03 | — | — | US | disclosed |
| US-20180118943-A1 | PH SENSITIVE FLUORESCENT PROBE | THE UNIVERSITY OF TOKYO (JP) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10815379-B2 | pH sensitive fluorescent probe | PHF6, PHF8, NHERF1 | ELANE 2822/4885MAPT 2293/4885KMT2A 2237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.