Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2009376 | 0.90 | HSD11B1 (0.84) | HSD11B1IDH1 | |
| SCHEMBL1971134 | 0.90 | HSD11B1 (0.84) | HSD11B1IDH1 | |
| Azd-4017 SCHEMBL1967349 | 0.88 | HSD11B1 (1.00) | HSD11B1IDH1 | |
| Azd-4017 SCHEMBL2006589 | 0.88 | HSD11B1 (1.00) | HSD11B1IDH1 | |
| Azd-4017 SCHEMBL1967884 | 0.88 | HSD11B1 (1.00) | HSD11B1IDH1 | |
| SCHEMBL3245313 | 0.88 | HSD11B1 (0.84) | HSD11B1IDH1 | |
| SCHEMBL14215682 | 0.85 | HSD11B1 (0.79) | HSD11B1IDH1 | |
| SCHEMBL1969653 | 0.85 | HSD11B1 (0.84) | HSD11B1IDH1 | |
| SCHEMBL26851808 | 0.84 | HSD11B1 (0.83) | HSD11B1IDH1 | |
| SCHEMBL13182706 | 0.84 | HSD11B1 (0.83) | HSD11B1IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180117065-A1 | PHARMACEUTICAL COMPOSITIONS FOR COMBINATION THERAPY | INTERCEPT PHARMACEUTICALS, INC. | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180117065-A1 | PHARMACEUTICAL COMPOSITIONS FOR COMBINATION THERAPY | GPR119, FABP1, SLC10A1 | HSD11B1 214/4885IDH1 2622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.