Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.50 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 8/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3131491 | 0.86 | MGLL (0.44) | MGLLGPR119FAAH | |
| SCHEMBL14646619 | 0.80 | PDK1 (0.59) | PDK1PDK2PDK3PDK4MGLL | |
| SCHEMBL3664002 | 0.79 | MGLL (0.49) | PDK1PDK2PDK3PDK4MGLL | |
| SCHEMBL3664004 | 0.79 | MGLL (0.49) | PDK1PDK2PDK3PDK4MGLL | |
| SCHEMBL7968974 | 0.79 | MGLL (0.49) | PDK1PDK2PDK3PDK4MGLL | |
| SCHEMBL953545 | 0.78 | PDK1 (0.70) | PDK1PDK2PDK3PDK4PARP1 | |
| SCHEMBL29300886 | 0.78 | PDK1 (0.70) | PDK1PDK2PDK3PDK4PARP1 | |
| SCHEMBL952361 | 0.78 | PDK1 (0.70) | PDK1PDK2PDK3PDK4PARP1 | |
| SCHEMBL2007646 | 0.78 | PDK1 (0.51) | PDK1PDK2PDK3PDK4MGLL | |
| SCHEMBL17954776 | 0.77 | PDK1 (0.50) | PDK1PDK2PDK3PDK4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964602-B2 | Biaryl compounds useful as agonists of the Gpr38 receptor | GLAXO GROUP LIMITED (GB) | 2011-06-21 | — | — | US | disclosed |