Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.56 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.56 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.56 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.56 |
| ▸ | PDE4A | P27815 | 1/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3075421 | 0.75 | ADORA2A (0.75) | PI4KAPI4K2BPI4K2API4KBPDE4A | |
| SCHEMBL637552 | 0.71 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBPDE4A | |
| SCHEMBL637551 | 0.71 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBPDE4A | |
| SCHEMBL3992023 | 0.71 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBPDE4A | |
| 4-Aminoquinazoline SCHEMBL142513 | 0.71 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBPDE4A | |
| SCHEMBL3951708 | 0.71 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBPDE4A | |
| SCHEMBL25620 | 0.71 | PDE4A (1.00) | PI4KAPI4K2BPI4K2API4KBPDE4A | |
| SCHEMBL11821044 | 0.71 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBPDE4A | |
| SCHEMBL276986 | 0.71 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBPDE4A | |
| SCHEMBL18087089 | 0.71 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103788085-A | 2-(quinazoline-4-amino)-5-thiazole carboxamide derivatives and biological medicine use thereof | UNIV FUDAN | 2014-05-14 | — | — | CN | claimed |
| CN-103784450-A | Micromolecular compound for inhibiting Src nonreceptor tyrosine kinase and pharmaceutical use thereof | UNIV FUDAN | 2014-05-14 | — | — | CN | claimed |
| CN-103420923-A | 4-aminoquinazolinehydroxamic acid compounds and applications thereof as antitumor medicaments | SINOPHARM YIXIN PHARMACEUTICAL CO LTD | 2013-12-04 | — | — | CN | claimed |
| CN-101857588-A | 4-aromatic aminoquinazoline derivative and purpose thereof | UNIV SOUTHEAST | 2010-10-13 | — | — | CN | claimed |
| EP-1976829-A2 | N-(6-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | GENELABS TECHNOLOGIES, INC. (US) | 2008-10-08 | — | — | EP | claimed |
| US-20070265262-A1 | N-(6-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | GENELABS TECHNOLOGIES, INC. | 2007-11-15 | — | — | US | claimed |
| WO-2007070556-A2 | N-(6-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | GENELABS TECHNOLOGIES, INC. (US) | 2007-06-21 | — | — | WO | claimed |
| US-20050130251-A1 | Reagent for determination of hydrogen peroxide | KYOWA MEDEX CO., LTD. (JP) | 2005-06-16 | — | — | US | claimed |
| EP-1424554-A1 | REAGENT FOR DETERMINING HYDROGEN PEROXIDE | KYOWA MEDEX CO., LTD. (JP) | 2004-06-02 | — | — | EP | claimed |
| US-9095565-B2 | Methods for treating blood disorders | PHOENICIA BIOSCIENCES, INC. (US) | 2015-08-04 | — | — | US | disclosed |
| US-20140301975-A1 | Methods for Treating Blood Disorders | PHOENICIA BIOSCIENCES INC (US) | 2014-10-09 | — | — | US | disclosed |
| US-8759378-B2 | Methods for treating blood disorders | PHOENICIA BIOSCIENCES, INC. (US) | 2014-06-24 | — | — | US | disclosed |
| CN-103420923-A | 4-aminoquinazolinehydroxamic acid compounds and applications thereof as antitumor medicaments | SINOPHARM YIXIN PHARMACEUTICAL CO LTD | 2013-12-04 | — | — | CN | disclosed |
| CN-101857588-B | 4-aromatic aminoquinazoline derivative and purpose thereof | UNIV SOUTHEAST | 2013-11-27 | — | — | CN | disclosed |
| US-20050130251-A1 | Reagent for determination of hydrogen peroxide | KYOWA MEDEX CO., LTD. (JP) | 2005-06-16 | — | — | US | disclosed |
| WO-2005023807-A2 | 4 - HETEROBICYCLYAMINO - SUBSTITUTED QUINAZOLINES AND ANALOGUES THEROF AS CAPSAICIN - ANTAGONISTS | NEUROGEN CORPORATION (US) | 2005-03-17 | — | — | WO | disclosed |
| EP-1424554-A1 | REAGENT FOR DETERMINING HYDROGEN PEROXIDE | KYOWA MEDEX CO., LTD. (JP) | 2004-06-02 | — | — | EP | disclosed |
| WO-1994011365-A1 | SUBSTITUTED BENZIMIDAZOLES AND QUINAZOLINES AS ANTIHYPERTENSIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-05-26 | — | — | WO | disclosed |
| US-4808715-A | HYPERTENSIVE AGENTS | JOHN WYETH & BROTHER LIMITED (GB) | 1989-02-28 | — | — | US | disclosed |
| US-4062844-A | Process for preparing hypotensive 2-(4-aroylpiperazin-1-yl)-amino-6,7-dimethoxyquinazolines | PFIZER INC. (US) | 1977-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265262-A1 | N-(6-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | ZC3HAV1, HAVCR2, ZC3HAV1L | PI4KA 4153/4885PI4K2B 3879/4885PI4K2A 4065/4885 |
| US-20140301975-A1 | Methods for Treating Blood Disorders | HBB, HBG1, HBG2 | PI4KA 4767/4885PI4K2B 4657/4885PI4K2A 4597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.