SCHEMBL20102455

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20111583	1.00	PTGDR2 (0.39)	PTGDR2APOBEC3GPTGDRALDH1A1HPGD
	SCHEMBL20102450	0.99	PTGDR2 (0.37)	PTGDR2APOBEC3GPTGDRALDH1A1HPGD
	SCHEMBL20102451	0.96	ALOX5AP (0.36)	PTGDR2ALOX5APFEN1CAMKK1CAMKK2
	SCHEMBL20102453	0.93	KDM1A (0.36)	PTGDR2APOBEC3GALDH1A1HPGDTSHR
	SCHEMBL20111344	0.90	PTGDR2 (0.32)	PTGDR2APOBEC3GPTGDRALDH1A1HPGD
	SCHEMBL20111581	0.89	PTGDR2 (0.37)	PTGDR2APOBEC3GPTGDRALDH1A1HPGD
	SCHEMBL20117597	0.89	ALDH1A1 (0.34)	ALDH1A1KDM1A
	SCHEMBL20102454	0.88	HTR1D (0.38)	PTGDR2PTGDRALOX5APFEN1
	SCHEMBL20111610	0.86	KDM1A (0.33)	PTGDR2APOBEC3GALDH1A1HPGDTSHR
	SCHEMBL20111290	0.86	PTGDR2 (0.37)	PTGDR2APOBEC3GPTGDRALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.