Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.32 |
| ▸ | RELA | Q04206 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2010600 | 1.00 | MAPK1 (0.35) | MAPK1NFKB1NFKB2RELAGAA | |
| SCHEMBL19520662 | 0.64 | MAPK1 (0.41) | MAPK1NFKB1NFKB2RELAGAA | |
| SCHEMBL21854629 | 0.63 | MAPK1 (0.37) | MAPK1NFKB1NFKB2RELAGAA | |
| SCHEMBL2155137 | 0.62 | MAPK1 (0.36) | MAPK1NFKB1NFKB2RELAGAA | |
| SCHEMBL2011204 | 0.61 | MAPK1 (0.36) | MAPK1NFKB1NFKB2RELAGAA | |
| SCHEMBL23007075 | 0.61 | NFKB1 (0.38) | MAPK1NFKB1NFKB2RELAGAA | |
| SCHEMBL27760177 | 0.61 | MAPK1 (0.38) | MAPK1GAA | |
| SCHEMBL321152 | 0.60 | MAPK1 (0.44) | MAPK1NFKB1NFKB2RELAGAA | |
| SCHEMBL17962577 | 0.60 | MAPK1 (0.37) | MAPK1NFKB1NFKB2RELAGAA | |
| SCHEMBL14718807 | 0.59 | MAPK1 (0.40) | MAPK1NFKB1NFKB2RELAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011067266-A1 | CARBOXYLIC ACID ANALOGS AS GLYCOGEN SYNTHASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-06-09 | — | — | WO | disclosed |