SCHEMBL2010262

SCHEMBL2010262

COC(=O)CCCCO[N+](=O)[O-]

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
LMNA P02545 2/20 0.43
ALDH1A1 P00352 1/20 0.43
ESR2 Q92731 2/20 0.40
PTGS2 P35354 1/20 0.38
RECQL P46063 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA4 P22748 1/20 0.38
CA9 Q16790 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2010947 0.98 TSHR (0.50) TSHRLMNAALDH1A1ESR2PTGS2
SCHEMBL14152352 0.98 TSHR (0.50) TSHRLMNAALDH1A1ESR2PTGS2
SCHEMBL2009498 0.98 TSHR (0.50) TSHRLMNAALDH1A1ESR2PTGS2
SCHEMBL2010998 0.98 TSHR (0.50) TSHRLMNAALDH1A1ESR2PTGS2
SCHEMBL2016061 0.98 TSHR (0.50) TSHRLMNAALDH1A1ESR2PTGS2
SCHEMBL2012153 0.98 TSHR (0.50) TSHRLMNAALDH1A1ESR2PTGS2
SCHEMBL2013628 0.94 TSHR (0.54) TSHRLMNAALDH1A1ESR2PTGS2
SCHEMBL2011016 0.86 TSHR (0.50) TSHRLMNAALDH1A1CA12
SCHEMBL2012707 0.81 CYP1A2 (0.48) TSHRALDH1A1ESR2PTGS2CA12
SCHEMBL10063280 0.81 CA12 (0.44) ALDH1A1ESR2PTGS2CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125379-A1 PRODRUG OF JAK KINASE INHIBITOR E NITIATE BIOPHARMACEUTICALS HANGZHOU CO LTD (CN) 2026-05-07 US disclosed
EP-4582425-A1 PRODRUG OF JAK KINASE INHIBITOR E-nitiate Biopharmaceuticals (Hangzhou) Co., Ltd (CN) 2025-07-09 EP disclosed
US-9365489-B2 Nitrooxy alkanoic acids and derivatives thereof in feed for reducing methane emission in ruminants, and/or to improve ruminant performance DSM IP ASSETS B.V. (NL) 2016-06-14 US disclosed
US-8784871-B2 Nitrooxy alkanoic acids and derivatives thereof in feed for reducing methane emission in ruminants, and/or to improve ruminant performance DSM IP ASSETS B.V. (NL) 2014-07-22 US disclosed
US-20140134282-A1 NITROOXY ALKANOIC ACIDS AND DERIVATIVES THEREOF IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE DSM IP ASSETS B.V. (NL) 2014-05-15 US disclosed
EP-2509435-B1 NITROOXY ALKANOIC ACIDS AND DERIVATIVES THEREOF IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE DSM IP ASSETS BV (NL) 2014-02-26 EP disclosed
US-20120315339-A1 NITROOXY ALKANOIC ACIDS AND DERIVATIVES THEREOF IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE DSM IP ASSETS B.V. (NL) 2012-12-13 US disclosed
EP-2509435-A1 NITROOXY ALKANOIC ACIDS AND DERIVATIVES THEREOF IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE DSM IP Assets B.V. (NL) 2012-10-17 EP disclosed
WO-2011070133-A1 NITROOXY ALKANOIC ACIDS AND DERIVATIVES THEREOF IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE DSM IP ASSETS B.V. (NL) 2011-06-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140134282-A1 NITROOXY ALKANOIC ACIDS AND DERIVATIVES THEREOF IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE PIGS, TECR, CYP4X1 TSHR 630/4885LMNA 901/4885ALDH1A1 2126/4885
US-20120315339-A1 NITROOXY ALKANOIC ACIDS AND DERIVATIVES THEREOF IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE PIGS, TECR, CYP4X1 TSHR 630/4885LMNA 901/4885ALDH1A1 2126/4885
US-20260125379-A1 PRODRUG OF JAK KINASE INHIBITOR JAK1, JAK2, JAK3 TSHR 519/4885LMNA 2664/4885ALDH1A1 1710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.