Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2010262 | 0.94 | TSHR (0.52) | TSHRLMNAALDH1A1ESR2PTGS2 | |
| SCHEMBL2010998 | 0.92 | TSHR (0.50) | TSHRLMNAALDH1A1ESR2KMT2A | |
| SCHEMBL2009498 | 0.92 | TSHR (0.50) | TSHRLMNAALDH1A1ESR2KMT2A | |
| SCHEMBL2010947 | 0.92 | TSHR (0.50) | TSHRLMNAALDH1A1ESR2KMT2A | |
| SCHEMBL2016061 | 0.92 | TSHR (0.50) | TSHRLMNAALDH1A1ESR2KMT2A | |
| SCHEMBL2012153 | 0.92 | TSHR (0.50) | TSHRLMNAALDH1A1ESR2KMT2A | |
| SCHEMBL14152352 | 0.92 | TSHR (0.50) | TSHRLMNAALDH1A1ESR2KMT2A | |
| SCHEMBL2011016 | 0.88 | TSHR (0.50) | TSHRLMNAALDH1A1MAPTMEN1 | |
| SCHEMBL2010912 | 0.81 | CYP1A2 (0.50) | TSHRALDH1A1MAPTPTGS2 | |
| SCHEMBL13979249 | 0.79 | PTGS2 (0.41) | ALDH1A1ESR2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12606525-B2 | Dimethyltryptamine analogues as nitric oxide delivery drugs | ATAI THERAPEUTICS, INC. (US) | 2026-04-21 | — | — | US | disclosed |
| US-20260028324-A1 | NITRIC OXIDE RELEASING PRODRUGS OF MDA AND MDMA | EMPATHBIO INC (US) | 2026-01-29 | — | — | US | disclosed |
| US-20240400511-A1 | DIMETHYLTRYPTAMINE ANALOGUES AS NITRIC OXIDE DELIVERY DRUGS | ATAI THERAPEUTICS, INC. | 2024-12-05 | — | — | US | disclosed |
| EP-4457214-A2 | DIMETHYLTRYPTAMINE ANALOGUES AS NITRIC OXIDE DELIVERY DRUGS | ATAI Therapeutics, Inc. (US) | 2024-11-06 | — | — | EP | disclosed |
| EP-4457222-A2 | NITRIC OXIDE RELEASING PRODRUGS OF MDA AND MDMA | EmpathBio, Inc. (US) | 2024-11-06 | — | — | EP | disclosed |
| US-12012381-B2 | Dimethyltryptamine analogues as nitric oxide delivery drugs | ATAI THERAPEUTICS, INC. (US) | 2024-06-18 | — | — | US | disclosed |
| US-11912680-B2 | Nitric oxide releasing prodrugs of MDA and MDMA | EMPATHBIO, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| US-11912680-B2 | Nitric oxide releasing prodrugs of MDA and MDMA | EMPATHBIO, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| US-20230227407-A1 | DIMETHYLTRYPTAMINE ANALOGUES AS NITRIC OXIDE DELIVERY DRUGS | ATAI THERAPEUTICS, INC. | 2023-07-20 | — | — | US | disclosed |
| US-20230227407-A1 | DIMETHYLTRYPTAMINE ANALOGUES AS NITRIC OXIDE DELIVERY DRUGS | ATAI THERAPEUTICS, INC. | 2023-07-20 | — | — | US | disclosed |
| US-8784871-B2 | Nitrooxy alkanoic acids and derivatives thereof in feed for reducing methane emission in ruminants, and/or to improve ruminant performance | DSM IP ASSETS B.V. (NL) | 2014-07-22 | — | — | US | disclosed |
| US-20140134282-A1 | NITROOXY ALKANOIC ACIDS AND DERIVATIVES THEREOF IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE | DSM IP ASSETS B.V. (NL) | 2014-05-15 | — | — | US | disclosed |
| EP-2509435-B1 | NITROOXY ALKANOIC ACIDS AND DERIVATIVES THEREOF IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE | DSM IP ASSETS BV (NL) | 2014-02-26 | — | — | EP | disclosed |
| US-20120315339-A1 | NITROOXY ALKANOIC ACIDS AND DERIVATIVES THEREOF IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE | DSM IP ASSETS B.V. (NL) | 2012-12-13 | — | — | US | disclosed |
| EP-2509435-A1 | NITROOXY ALKANOIC ACIDS AND DERIVATIVES THEREOF IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE | DSM IP Assets B.V. (NL) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011101245-A1 | NITRIC OXIDE RELEASING COMPOUNDS FOR THE TREATMENT OF NEUROPATHIC PAIN | NICOX S.A. (FR) | 2011-08-25 | — | — | WO | disclosed |
| WO-2011092065-A1 | NITRIC OXIDE RELEASING COMPOUNDS FOR THE TREATMENT OF NEUROPHATIC PAIN | NICOX S.A. (FR) | 2011-08-04 | — | — | WO | disclosed |
| WO-2011070133-A1 | NITROOXY ALKANOIC ACIDS AND DERIVATIVES THEREOF IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE | DSM IP ASSETS B.V. (NL) | 2011-06-16 | — | — | WO | disclosed |
| US-20110130375-A1 | NEW NO-RELEASING STEROIDS FOR THE TREATMENT OF RETINA AND MACULA LUTEA DISEASES | NICOX S.A. (FR) | 2011-06-02 | — | — | US | disclosed |
| WO-2009136281-A1 | NITRIC OXIDE DONATING PROSTAMIDES | NICOX S.A. (FR) | 2009-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140134282-A1 | NITROOXY ALKANOIC ACIDS AND DERIVATIVES THEREOF IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE | PIGS, TECR, CYP4X1 | TSHR 630/4885LMNA 901/4885ALDH1A1 2126/4885 |
| US-20230227407-A1 | DIMETHYLTRYPTAMINE ANALOGUES AS NITRIC OXIDE DELIVERY DRUGS | NOS2, NOS1, NOS3 | TSHR 1484/4885LMNA 3271/4885ALDH1A1 860/4885 |
| US-20120315339-A1 | NITROOXY ALKANOIC ACIDS AND DERIVATIVES THEREOF IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE | PIGS, TECR, CYP4X1 | TSHR 630/4885LMNA 901/4885ALDH1A1 2126/4885 |
| US-20110130375-A1 | NEW NO-RELEASING STEROIDS FOR THE TREATMENT OF RETINA AND MACULA LUTEA DISEASES | LHCGR, NR5A1, LSS | TSHR 345/4885LMNA 1163/4885ALDH1A1 2367/4885 |
| US-20260028324-A1 | NITRIC OXIDE RELEASING PRODRUGS OF MDA AND MDMA | DBH, SLC6A3, SLC6A2 | TSHR 216/4885LMNA 1614/4885ALDH1A1 601/4885 |
| US-20240400511-A1 | DIMETHYLTRYPTAMINE ANALOGUES AS NITRIC OXIDE DELIVERY DRUGS | NOS2, NOS1, NOS3 | TSHR 1484/4885LMNA 3271/4885ALDH1A1 860/4885 |
| US-12012381-B2 | Dimethyltryptamine analogues as nitric oxide delivery drugs | NOS2, NOS1, NOS3 | TSHR 1484/4885LMNA 3271/4885ALDH1A1 860/4885 |
| US-11912680-B2 | Nitric oxide releasing prodrugs of MDA and MDMA | NOS1, NOS3, NOS2 | TSHR 1505/4885LMNA 3995/4885ALDH1A1 185/4885 |
| US-12606525-B2 | Dimethyltryptamine analogues as nitric oxide delivery drugs | TPH1, TPH2, SLC6A4 | TSHR 683/4885LMNA 2727/4885ALDH1A1 1116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.