Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 7/20 | 0.66 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 4/20 | 0.36 |
| ▸ | SLC16A1 | P53985 | 4/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2013138 | 0.93 | MLNR (0.65) | MLNRMGLLCXCR3PDK1PDK2 | |
| SCHEMBL3134434 | 0.91 | MLNR (0.73) | MLNRMGLLHRH3SLC16A3SLC16A1 | |
| SCHEMBL3138321 | 0.83 | MLNR (0.72) | MLNRMGLL | |
| SCHEMBL2010303 | 0.81 | MLNR (0.63) | MLNRHRH3SLC16A3SLC16A1 | |
| SCHEMBL2009345 | 0.80 | MLNR (1.00) | MLNR | |
| SCHEMBL2009415 | 0.80 | MLNR (1.00) | MLNRSLC6A4SLC6A3 | |
| SCHEMBL4690685 | 0.80 | MLNR (1.00) | MLNRSLC6A4SLC6A3 | |
| SCHEMBL2012520 | 0.75 | MLNR (0.63) | MLNRHRH3SLC16A3SLC16A1 | |
| SCHEMBL2007837 | 0.74 | MLNR (0.73) | MLNRHRH3 | |
| SCHEMBL2013140 | 0.74 | MLNR (0.61) | MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964602-B2 | Biaryl compounds useful as agonists of the Gpr38 receptor | GLAXO GROUP LIMITED (GB) | 2011-06-21 | — | — | US | disclosed |