Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 7/20 | 0.65 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2010301 | 0.93 | MLNR (0.66) | MLNRMGLLCXCR3PDK1PDK2 | |
| SCHEMBL3138321 | 0.90 | MLNR (0.72) | MLNRMGLLCCR1ALDH1A1KMT2A | |
| SCHEMBL3134434 | 0.83 | MLNR (0.73) | MLNRMGLL | |
| SCHEMBL2007837 | 0.81 | MLNR (0.73) | MLNRALDH1A1KMT2A | |
| SCHEMBL2013140 | 0.81 | MLNR (0.61) | MLNRALDH1A1KMT2A | |
| SCHEMBL3128327 | 0.79 | MLNR (0.85) | MLNRCHRM4 | |
| SCHEMBL2012437 | 0.72 | MLNR (1.00) | MLNR | |
| SCHEMBL2010214 | 0.71 | MLNR (0.46) | MLNRPDK1PDK2PDK3PDK4 | |
| SCHEMBL2008090 | 0.70 | MLNR (0.73) | MLNR | |
| SCHEMBL2010191 | 0.69 | PDK1 (0.50) | MGLLPDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964602-B2 | Biaryl compounds useful as agonists of the Gpr38 receptor | GLAXO GROUP LIMITED (GB) | 2011-06-21 | — | — | US | disclosed |