Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 8/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6745557 | 0.75 | TRPV4 (0.39) | TRPV4ARIDO1SLC22A12CYP11B2 | |
| SCHEMBL73332 | 0.62 | — | — | |
| SCHEMBL29517818 | 0.62 | — | — | |
| Water SCHEMBL27523013 | 0.62 | TSHR (0.50) | TRPV4ARSLC22A12VCAM1DYRK1A | |
| Sulfuric Acid SCHEMBL11781652 | 0.62 | SLC22A12 (0.47) | TRPV4S1PR3SLC22A12ALDH1A1 | |
| Methyl Alcohol SCHEMBL28872632 | 0.62 | TSHR (0.50) | TRPV4ARSLC22A12DYRK1AALDH1A1 | |
| Acetic Acid SCHEMBL11875044 | 0.61 | KDM4E (0.44) | S1PR3SLC22A12ALDH1A1 | |
| SCHEMBL473963 | 0.61 | TRPV4 (0.57) | TRPV4ARIDO1CYP11B2 | |
| Boric Acid SCHEMBL29171863 | 0.61 | TSHR (0.43) | TRPV4ARS1PR3SLC22A12DYRK1A | |
| Hydrochloric Acid SCHEMBL31061044 | 0.61 | TSHR (0.48) | TRPV4ARSLC22A12VCAM1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118718-A1 | Substituted Quinoxaline Derivatives | SELVITA S.A. (PL) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118718-A1 | Substituted Quinoxaline Derivatives | BRCA1, NQO2, NQO1 | TRPV4 4561/4885AR 4206/4885IDO1 1270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.