Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GYS1 | P13807 | 11/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2009950 | 0.92 | GYS1 (0.53) | GYS1MAOBPPARAF10CYP2C9 | |
| SCHEMBL2010321 | 0.82 | GYS1 (0.46) | GYS1MAOBPPARASLC2A1 | |
| SCHEMBL2011184 | 0.73 | GYS1 (0.57) | GYS1MAOBF10 | |
| SCHEMBL2012650 | 0.73 | GYS1 (0.53) | GYS1MAOBPPARACYP2C9PPARG | |
| Hydrochloric Acid SCHEMBL2014675 | 0.73 | GYS1 (0.56) | GYS1MAOBF10 | |
| SCHEMBL2011587 | 0.72 | GYS1 (0.75) | GYS1MAOBPPARACYP2C9PPARG | |
| SCHEMBL2009949 | 0.72 | GYS1 (0.53) | GYS1MAOBPPARA | |
| SCHEMBL2012329 | 0.71 | GYS1 (0.52) | GYS1PPARASLC2A1RAB9A | |
| SCHEMBL2037268 | 0.70 | GYS1 (0.81) | GYS1 | |
| SCHEMBL2009810 | 0.70 | GYS1 (0.69) | GYS1MAOBPPARAF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011067266-A1 | CARBOXYLIC ACID ANALOGS AS GLYCOGEN SYNTHASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-06-09 | — | — | WO | disclosed |