Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 14/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20103408 | 0.85 | OPRL1 (0.32) | MAOBMAOAOPRL1 | |
| SCHEMBL20103475 | 0.76 | FFAR1 (0.43) | — | |
| SCHEMBL18295013 | 0.74 | SOS1 (0.40) | OPRL1 | |
| SCHEMBL20103295 | 0.74 | FFAR1 (0.48) | — | |
| SCHEMBL20103372 | 0.74 | ESR1 (0.39) | OPRL1 | |
| SCHEMBL21644870 | 0.74 | ESR1 (0.39) | OPRL1 | |
| SCHEMBL20103549 | 0.73 | FFAR1 (0.52) | — | |
| SCHEMBL20103371 | 0.71 | LNPEP (0.35) | — | |
| SCHEMBL14297935 | 0.69 | BACE1 (0.44) | OPRL1 | |
| SCHEMBL765783 | 0.69 | BACE1 (0.41) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081047-A1 | CYCLOHEXYL GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |