Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 8/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20103318 | 0.85 | MAOB (0.35) | OPRL1MAOAMAOB | |
| SCHEMBL18295013 | 0.73 | SOS1 (0.40) | OPRL1KDM1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20103295 | 0.73 | FFAR1 (0.48) | FFAR1 | |
| SCHEMBL20103372 | 0.72 | ESR1 (0.39) | OPRL1FFAR1NUDT1BACE1 | |
| SCHEMBL21644870 | 0.72 | ESR1 (0.39) | OPRL1FFAR1NUDT1BACE1 | |
| SCHEMBL20103549 | 0.71 | FFAR1 (0.52) | FFAR1 | |
| SCHEMBL20103475 | 0.71 | FFAR1 (0.43) | FFAR1 | |
| SCHEMBL14297935 | 0.68 | BACE1 (0.44) | OPRL1NUDT1BACE1 | |
| SCHEMBL765783 | 0.68 | BACE1 (0.41) | OPRL1KDM1ANUDT1BACE1 | |
| SCHEMBL14314452 | 0.66 | NUDT1 (0.46) | OPRL1NUDT1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081047-A1 | CYCLOHEXYL GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |