SCHEMBL20103364

SCHEMBL20103364

COC(=O)C(C)[C@H](c1cccc(O)c1)C1CC1

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 18/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15990271 1.00 FFAR1 (0.49) FFAR1
SCHEMBL15971969 1.00 FFAR1 (0.49) FFAR1
SCHEMBL29377553 1.00 FFAR1 (0.49) FFAR1
SCHEMBL17503182 1.00 FFAR1 (0.49) FFAR1
SCHEMBL15973334 1.00 FFAR1 (0.49) FFAR1
SCHEMBL19175526 1.00 FFAR1 (0.49) FFAR1
SCHEMBL17537791 0.95 FFAR1 (0.45) FFAR1
SCHEMBL19201873 0.95 FFAR1 (0.45) FFAR1
SCHEMBL17408842 0.86 FFAR1 (0.45) FFAR1
SCHEMBL22717214 0.85 FFAR1 (0.49) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018081047-A1 CYCLOHEXYL GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES JANSSEN PHARMACEUTICA NV (BE) 2018-05-03 WO disclosed