SCHEMBL29377553

SCHEMBL29377553

COC(=O)[C@@H](C)[C@H](c1cccc(O)c1)C1CC1

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 18/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20103364 1.00 FFAR1 (0.49) FFAR1
SCHEMBL15990271 1.00 FFAR1 (0.49) FFAR1
SCHEMBL15971969 1.00 FFAR1 (0.49) FFAR1
SCHEMBL17503182 1.00 FFAR1 (0.49) FFAR1
SCHEMBL15973334 1.00 FFAR1 (0.49) FFAR1
SCHEMBL19175526 1.00 FFAR1 (0.49) FFAR1
SCHEMBL17537791 0.95 FFAR1 (0.45) FFAR1
SCHEMBL19201873 0.95 FFAR1 (0.45) FFAR1
SCHEMBL17408842 0.86 FFAR1 (0.45) FFAR1
SCHEMBL22717214 0.85 FFAR1 (0.49) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2958562-B1 ANTIDIABETIC BICYCLIC COMPOUNDS MERCK SHARP & DOHME LLC (US) 2025-09-10 EP disclosed
US-20250223281-A1 ANTIDIABETIC COMPOUNDS AND COMPOSITIONS REZUBIO PHARMACEUTICALS CO., LTD (CN) 2025-07-10 US disclosed
EP-4463451-A1 ANTIDIABETIC COMPOUNDS AND COMPOSITIONS Rezubio Pharmaceuticals Co., Ltd (CN) 2024-11-20 EP disclosed
WO-2023134712-A1 ANTIDIABETIC COMPOUNDS AND COMPOSITIONS REZUBIO PHARMACEUTICALS CO., LTD (CN) 2023-07-20 WO disclosed
US-20220226298-A1 GPR40 AGONISTS KALLYOPE, INC. 2022-07-21 US disclosed
EP-3976576-A1 GPR40 AGONISTS Kallyope, Inc. (US) 2022-04-06 EP disclosed
WO-2022028317-A1 ANTIDIABETIC COMPOUNDS AND COMPOSITIONS REZUBIO PHARMACEUTICALS CO., LTD (CN) 2022-02-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220226298-A1 GPR40 AGONISTS GPR119, GPR65, GLP1R FFAR1 10/4885
US-20250223281-A1 ANTIDIABETIC COMPOUNDS AND COMPOSITIONS GPR119, GLP1R, GPR65 FFAR1 28/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.