Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.35 |
| ▸ | CDK9 | P50750 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20103308 | 0.81 | CCNT1 (0.42) | ESR2TLR9TLR8TLR7CCNT1 | |
| SCHEMBL20103515 | 0.77 | ESR2 (0.47) | ESR2CCNT1CDK9 | |
| SCHEMBL20103296 | 0.71 | ESR2 (0.46) | ESR2CCNT1CDK9 | |
| SCHEMBL18180513 | 0.68 | ESR2 (0.45) | ESR2CCNT1CDK9 | |
| SCHEMBL20103382 | 0.66 | ESR2 (0.46) | ESR2CCNT1CDK9 | |
| SCHEMBL12186319 | 0.63 | ESR2 (0.47) | ESR2 | |
| SCHEMBL1983631 | 0.63 | — | — | |
| SCHEMBL14733413 | 0.63 | — | — | |
| SCHEMBL9406310 | 0.62 | ESR2 (0.39) | ESR2CCNT1CDK9 | |
| SCHEMBL21688373 | 0.61 | CDK9 (0.56) | CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081047-A1 | CYCLOHEXYL GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |