Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 20/20 | 1.00 |
| ▸ | NTRK2 | Q16620 | 18/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28095814 | 0.77 | KDR (0.68) | NTRK1NTRK2 | |
| SCHEMBL20103636 | 0.75 | NTRK1 (1.00) | NTRK1NTRK2 | |
| SCHEMBL4106743 | 0.75 | MEN1 (0.66) | NTRK1NTRK2 | |
| SCHEMBL14451618 | 0.73 | NPC1 (0.67) | NTRK1NTRK2 | |
| SCHEMBL17976408 | 0.72 | MEN1 (0.66) | NTRK1NTRK2 | |
| SCHEMBL4116578 | 0.72 | MEN1 (0.70) | — | |
| SCHEMBL7018167 | 0.71 | NTRK1 (0.59) | NTRK1NTRK2 | |
| SCHEMBL14451603 | 0.71 | GAA (0.64) | NTRK1NTRK2 | |
| SCHEMBL17975955 | 0.71 | MEN1 (0.72) | — | |
| SCHEMBL29200429 | 0.71 | MEN1 (0.72) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3315495-A1 | N,N' -DIARYLUREA, N,N' -DIARYLTHIOUREA AND N,N' -DIARYLGUANIDINO COMPOUNDS FOR USE IN TREATMENT AND PREVENTION OF INFLAMMATORY DISEASE | Universität Innsbruck (AT) | 2018-05-02 | — | — | EP | disclosed |