Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21688303 | 1.00 | FFAR1 (0.46) | FFAR1PDK1PDK2PDK3PDK4 | |
| SCHEMBL20103560 | 0.89 | FFAR1 (0.44) | FFAR1CTRB1MEN1KMT2AEPHX1 | |
| SCHEMBL21644939 | 0.88 | FFAR1 (0.49) | FFAR1PDK1PDK2PDK3PDK4 | |
| SCHEMBL21644942 | 0.88 | FFAR1 (0.49) | FFAR1PDK1PDK2PDK3PDK4 | |
| SCHEMBL20103648 | 0.85 | FFAR1 (0.41) | FFAR1CTRB1MEN1KMT2A | |
| SCHEMBL20103443 | 0.84 | FFAR1 (0.44) | FFAR1 | |
| SCHEMBL20103446 | 0.84 | FFAR1 (0.44) | FFAR1 | |
| SCHEMBL20103527 | 0.84 | FFAR1 (0.44) | FFAR1 | |
| SCHEMBL20103672 | 0.83 | FFAR1 (0.57) | FFAR1PDK1PDK2PDK3PDK4 | |
| SCHEMBL21688395 | 0.83 | FFAR1 (0.43) | FFAR1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081047-A1 | CYCLOHEXYL GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |