Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.41 |
| ▸ | PGK1 | P00558 | 4/20 | 0.36 |
| ▸ | PGK2 | P07205 | 4/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.32 |
| ▸ | ACP3 | P15309 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21644920 | 0.90 | FFAR1 (0.48) | FFAR1PGK1PGK2ACP3MEN1 | |
| SCHEMBL21644921 | 0.90 | FFAR1 (0.48) | FFAR1PGK1PGK2ACP3MEN1 | |
| SCHEMBL21688303 | 0.85 | FFAR1 (0.46) | FFAR1CTRB1MEN1KMT2A | |
| SCHEMBL20103532 | 0.85 | FFAR1 (0.46) | FFAR1CTRB1MEN1KMT2A | |
| SCHEMBL20103560 | 0.84 | FFAR1 (0.44) | FFAR1CTRB1MEN1KMT2A | |
| SCHEMBL20103443 | 0.79 | FFAR1 (0.44) | FFAR1 | |
| SCHEMBL20103527 | 0.79 | FFAR1 (0.44) | FFAR1 | |
| SCHEMBL20103446 | 0.79 | FFAR1 (0.44) | FFAR1 | |
| SCHEMBL21688395 | 0.78 | FFAR1 (0.43) | FFAR1 | |
| SCHEMBL20103672 | 0.78 | FFAR1 (0.57) | FFAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081047-A1 | CYCLOHEXYL GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |