Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20103584 | 0.84 | FFAR1 (0.66) | FFAR1POLBMEN1ALDH1A1MAPK1 | |
| SCHEMBL20103672 | 0.83 | FFAR1 (0.57) | FFAR1POLBMEN1ALDH1A1MAPK1 | |
| SCHEMBL20103441 | 0.79 | FFAR1 (0.67) | FFAR1 | |
| SCHEMBL20103439 | 0.78 | FFAR1 (0.66) | FFAR1 | |
| SCHEMBL27730686 | 0.76 | POLB (0.50) | FFAR1POLBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16320729 | 0.74 | AOC3 (0.46) | POLBSLC6A2SLC6A4SLC6A3AOC3 | |
| SCHEMBL28787874 | 0.74 | AOC3 (0.54) | FFAR1POLBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20738700 | 0.70 | TAAR1 (0.51) | POLBAOC3MEN1ALDH1A1KMT2A | |
| SCHEMBL21645004 | 0.70 | FFAR1 (0.53) | FFAR1 | |
| SCHEMBL21645002 | 0.70 | FFAR1 (0.53) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081047-A1 | CYCLOHEXYL GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |