Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11809259 | 0.72 | TAAR1 (0.32) | TAAR1HTR3ATSHRNFKB1HIF1A | |
| SCHEMBL7146853 | 0.69 | TSHR (0.31) | TAAR1HTR3ATSHRNFKB1HIF1A | |
| SCHEMBL5735343 | 0.68 | TSHR (0.46) | TAAR1HTR3ATSHRNFKB1HIF1A | |
| Hydrochloric Acid SCHEMBL4857186 | 0.68 | ALOX15 (0.32) | TSHRHIF1AKDM4EALOX15APEX1 | |
| SCHEMBL17048947 | 0.67 | — | — | |
| SCHEMBL3705866 | 0.63 | SMN1; SMN2 (0.42) | TAAR1HTR3ATSHRNFKB1HIF1A | |
| SCHEMBL11196912 | 0.63 | APEX1 (0.36) | TAAR1HTR3ATSHRNFKB1HIF1A | |
| SCHEMBL8880562 | 0.63 | TAAR1 (0.35) | TAAR1HTR3ATSHRNFKB1HIF1A | |
| SCHEMBL19736660 | 0.63 | MAPT (0.40) | TAAR1HTR3ATSHRNFKB1HIF1A | |
| SCHEMBL14074122 | 0.60 | TAAR1 (0.35) | TAAR1HTR3ATSHRNFKB1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3110810-B1 | PYRAZOLE AMIDE DERIVATIVE | TEIJIN PHARMA LTD (JP) | 2018-05-02 | — | — | EP | disclosed |