Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | APEX1 | P27695 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 3/20 | 0.35 |
| ▸ | BLM | P54132 | 3/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19736663 | 0.83 | ALDH1A1 (0.38) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL19736764 | 0.82 | ALDH1A1 (0.36) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL15801329 | 0.76 | ALDH1A1 (0.35) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL14164522 | 0.73 | BLM (0.47) | MAPTALDH1A1KDM4ELMNASLC6A2 | |
| SCHEMBL19736675 | 0.72 | TAAR1 (0.33) | MAPTKDM4ELMNAHSD17B10ALOX15 | |
| SCHEMBL19736678 | 0.71 | NOS2 (0.38) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL21753734 | 0.70 | ALDH1A1 (0.50) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL25162024 | 0.69 | ALDH1A1 (0.43) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL19736661 | 0.68 | ALDH1A1 (0.35) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL19736762 | 0.67 | ALDH1A1 (0.34) | MAPTALDH1A1KDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11345653-B2 | Compositions and methods for reactivating cholinesterases | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE INC. (US) | 2022-05-31 | — | — | US | disclosed |
| US-20190345097-A1 | Compositions and Methods for Reactivating Cholinesterases | The Henry M. Jackson Foundation for the Advancemen t of Military Medicine, Inc. (US) | 2019-11-14 | — | — | US | disclosed |
| WO-2017218886-A1 | COMPOSITIONS AND METHODS FOR REACTIVATING CHOLINESTERASES | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (US) | 2017-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11345653-B2 | Compositions and methods for reactivating cholinesterases | ACHE, BCHE, CHAT | MAPT 1020/4885ALDH1A1 735/4885KDM4E 409/4885 |
| US-20190345097-A1 | Compositions and Methods for Reactivating Cholinesterases | ACHE, BCHE, CHAT | MAPT 1020/4885ALDH1A1 735/4885KDM4E 409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.