Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | PPM1B | O75688 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20103730 | 1.00 | SMYD3 (0.40) | SMYD3PPM1BPTPN1PPP1CCMAPT | |
| SCHEMBL17118105 | 0.81 | MAPT (0.41) | PPM1BPTPN1PPP1CCMAPTCYP3A4 | |
| SCHEMBL13825965 | 0.80 | ATM (0.36) | PPM1BPTPN1PPP1CCMAPTCYP3A4 | |
| SCHEMBL20825935 | 0.80 | ATM (0.36) | PPM1BPTPN1PPP1CCMAPTCYP3A4 | |
| SCHEMBL22189923 | 0.80 | ATM (0.36) | PPM1BPTPN1PPP1CCMAPTCYP3A4 | |
| SCHEMBL20818751 | 0.80 | ATM (0.36) | PPM1BPTPN1PPP1CCMAPTCYP3A4 | |
| SCHEMBL294716 | 0.79 | LMNA (0.43) | PPM1BPTPN1PPP1CCMAPTCYP3A4 | |
| Hydrochloric Acid SCHEMBL17098802 | 0.78 | SMYD3 (0.37) | SMYD3PPM1BPTPN1PPP1CCMAPT | |
| Hydrochloric Acid SCHEMBL17098800 | 0.78 | SMYD3 (0.37) | SMYD3PPM1BPTPN1PPP1CCMAPT | |
| Hydrochloric Acid SCHEMBL17098804 | 0.78 | SMYD3 (0.37) | SMYD3PPM1BPTPN1PPP1CCMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3110810-B1 | PYRAZOLE AMIDE DERIVATIVE | TEIJIN PHARMA LTD (JP) | 2018-05-02 | — | — | EP | disclosed |