Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PPM1B | O75688 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27709106 | 0.92 | LMNA (0.39) | LMNAMAPTALDH1A1HSD17B10GAA | |
| SCHEMBL7806653 | 0.92 | GAA (0.39) | LMNAMAPTALDH1A1HSD17B10GAA | |
| SCHEMBL294867 | 0.83 | PPM1B (0.42) | ALDH1A1PPM1BPTPN1PPP1CC | |
| SCHEMBL11042018 | 0.83 | CYP1A2 (0.41) | LMNAMAPTALDH1A1HSD17B10GAA | |
| SCHEMBL16409442 | 0.83 | LMNA (0.41) | LMNAMAPTALDH1A1HSD17B10GAA | |
| SCHEMBL17118105 | 0.81 | MAPT (0.41) | LMNAMAPTALDH1A1GAACYP3A4 | |
| SCHEMBL3691417 | 0.80 | ALDH1A1 (0.47) | LMNAMAPTALDH1A1HSD17B10GAA | |
| SCHEMBL6574520 | 0.80 | MAPT (0.40) | LMNAMAPTALDH1A1HSD17B10GAA | |
| SCHEMBL24766727 | 0.79 | LMNA (0.39) | LMNAMAPTALDH1A1HSD17B10GAA | |
| SCHEMBL5316981 | 0.79 | HTT (0.41) | MAPTALDH1A1GAACYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112501217-A | Continuous preparation method of S- (+) -2, 2-dimethylcyclopropane carboxylic acid | 天津凯莱英制药有限公司 | 2021-03-16 | — | — | CN | claimed |
| CN-115896065-A | Stereoselective carboxylesterase, encoding gene, vector and application thereof | 江南大学 | 2023-04-04 | — | — | CN | disclosed |
| CN-115141871-A | Preparation method of peramivir intermediate | 福建未来药业有限公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-112501217-A | Continuous preparation method of S- (+) -2, 2-dimethylcyclopropane carboxylic acid | 天津凯莱英制药有限公司 | 2021-03-16 | — | — | CN | disclosed |
| CN-111470996-A | Purification method of S- (+) -2, 2-dimethyl cyclopropane carboxamide | 新乡市锦源化工有限公司 | 2020-07-31 | — | — | CN | disclosed |
| CN-111107846-A | Heteroaryl allosteric modulators of nicotinic acetylcholine receptors | 默沙东公司 | 2020-05-05 | — | — | CN | disclosed |
| CN-104178469-B | Cyclopropane formate hydrolase, gene, mutant and application thereof | 华东理工大学 | 2017-01-25 | — | — | CN | disclosed |
| US-8822724-B2 | Method for producing carboxylic acid amide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-09-02 | — | — | US | disclosed |
| EP-2599769-A1 | METHOD FOR PRODUCING CARBOXYLIC ACID AMIDE | Sumitomo Chemical Company Limited (JP) | 2013-06-05 | — | — | EP | disclosed |
| US-20130123505-A1 | METHOD FOR PRODUCING CARBOXYLIC ACID AMIDE | SUMITOMO CHEMICAL COMPANY, LIMITED | 2013-05-16 | — | — | US | disclosed |
| US-20020004618-A1 | Chiral copper complex and production processes thereof and using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-01-10 | — | — | US | disclosed |
| US-20010037036-A1 | Chiral copper complex catalyst composition and asymmetric production process using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-11-01 | — | — | US | disclosed |
| CN-1313277-A | Chiral copper complex, preparation method and application thereof | SUMITOMO CHEMICAL CO (JP) | 2001-09-19 | — | — | CN | disclosed |
| EP-1120402-A2 | Chiral copper complex and production processes thereof and using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-08-01 | — | — | EP | disclosed |
| CN-1068583-C | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL MYERS SQUIBB CO (US) | 2001-07-18 | — | — | CN | disclosed |
| CN-1143628-A | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL MYERS SQUIBB CO (US) | 1997-02-26 | — | — | CN | disclosed |
| EP-0128012-B1 | NOVEL CHIRAL COPPER COMPLEX AND ASYMMETRIC SYNTHESIS OF CYCLOPROPANECARBOXYLATE DERIVATIVES USING SAID COMPLEX AS CATALYST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-11-20 | — | — | EP | disclosed |
| US-4603218-A | Asymmetric synthesis of cyclopropanecarboxylate derivatives using chiral copper complex as catalyst | SUMITOMO CHEMICAL CO., LTD. (JP) | 1986-07-29 | — | — | US | disclosed |
| US-4552972-A | Chiral copper complex | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-11-12 | — | — | US | disclosed |
| EP-0128012-A2 | Novel chiral copper complex and asymmetric synthesis of cyclopropanecarboxylate derivatives using said complex as catalyst | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-12-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010037036-A1 | Chiral copper complex catalyst composition and asymmetric production process using the same | AP1M1, UBA3, AP1S1 | LMNA 4316/4885MAPT 3699/4885ALDH1A1 254/4885 |
| US-20130123505-A1 | METHOD FOR PRODUCING CARBOXYLIC ACID AMIDE | HCAR2, NAAA, FAAH2 | LMNA 3379/4885MAPT 3830/4885ALDH1A1 161/4885 |
| US-20020004618-A1 | Chiral copper complex and production processes thereof and using the same | SOD1, XDH, NFXL1 | LMNA 4559/4885MAPT 4234/4885ALDH1A1 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.