Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.34 |
| ▸ | KDM6B | O15054 | 4/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16684319 | 0.72 | KDM4C (0.41) | KDM4CKDM6BKDM4EALDH1A1GLA | |
| SCHEMBL19840668 | 0.72 | KDM4C (0.44) | KDM4CKDM6BKDM4EALDH1A1GLA | |
| SCHEMBL14618137 | 0.72 | KDM4C (0.44) | KDM4CKDM6BSLC6A2SLC6A4KDM4E | |
| Bromide SCHEMBL16671695 | 0.71 | KDM4C (0.40) | KDM4CKDM6BKDM4EALDH1A1GLA | |
| SCHEMBL9846115 | 0.70 | KDM4C (0.35) | KDM4CKDM6BSLC22A12KDM4EALDH1A1 | |
| SCHEMBL115648 | 0.70 | KDM4C (0.56) | KDM4CKDM6BKDM4EALDH1A1TDP1 | |
| SCHEMBL30100781 | 0.70 | KDM4C (0.56) | KDM4CKDM6BKDM4EALDH1A1TDP1 | |
| SCHEMBL11236770 | 0.70 | KDM4C (0.44) | KDM4CKDM6BKDM4EALDH1A1GLA | |
| SCHEMBL20104091 | 0.69 | GAA (0.31) | GAA | |
| SCHEMBL3025518 | 0.69 | KDM4C (0.44) | KDM4CKDM6BKDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3110810-B1 | PYRAZOLE AMIDE DERIVATIVE | TEIJIN PHARMA LTD (JP) | 2018-05-02 | — | — | EP | disclosed |