SCHEMBL9846115

SCHEMBL9846115

CCc1cnccc1C(=O)CCC(C)CC(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 6/20 0.35
KDM6B O15054 3/20 0.35
EGFR P00533 1/20 0.31
SLC22A12 Q96S37 1/20 0.30
LMNA P02545 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
TRPV1 Q8NER1 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GLA P06280 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19840668 0.77 KDM4C (0.44) KDM4CKDM6BLMNASMN1; SMN2L3MBTL1
SCHEMBL9846137 0.76 CYP2E1 (0.34) LMNASMN1; SMN2L3MBTL1
SCHEMBL9846363 0.72 KDM4C (0.36) KDM4CKDM6BLMNASMN1; SMN2L3MBTL1
SCHEMBL11233677 0.71 MAP4K1 (0.40) KDM4CKDM6BL3MBTL1KDM4EALDH1A1
SCHEMBL16684319 0.70 KDM4C (0.41) KDM4CKDM6BLMNASMN1; SMN2L3MBTL1
SCHEMBL20104059 0.70 KDM4C (0.34) KDM4CKDM6BSLC22A12LMNAL3MBTL1
SCHEMBL9846210 0.70 GALR3 (0.36) KDM4CKDM6BTRPV1KDM4EALDH1A1
Bromide SCHEMBL16671695 0.69 KDM4C (0.40) KDM4CKDM6BLMNASMN1; SMN2L3MBTL1
SCHEMBL9846279 0.69 GPBAR1 (0.36)
SCHEMBL11236770 0.68 KDM4C (0.44) KDM4CKDM6BLMNASMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0424538-A1 PYRIDINE DERIVATIVES AND THEIR SALTS, AND INSECTICIDAL/ACARICIDAL AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-05-02 EP disclosed