SCHEMBL20104219

SCHEMBL20104219

C=C(C)C1CCC(C)CC1C

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.35
TRPA1 O75762 2/20 0.33
TRPM8 Q7Z2W7 2/20 0.33
EPHX1 P07099 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19058480 0.85 CES2 (0.37) CES2TRPA1TRPM8EPHX1
SCHEMBL18807613 0.84 EPHX1 (0.36) CES2TRPA1TRPM8EPHX1L3MBTL1
SCHEMBL25404332 0.83
SCHEMBL25404335 0.83
Isopulegol SCHEMBL8815381 0.80 TRPA1 (0.45) CES2TRPA1TRPM8EPHX1
SCHEMBL24538452 0.80 TRPA1 (0.31) TRPA1TRPM8EPHX1
Isopulegol SCHEMBL20903638 0.80 TRPA1 (0.45) CES2TRPA1TRPM8EPHX1
Isopulegol SCHEMBL20903648 0.80 TRPA1 (0.45) CES2TRPA1TRPM8EPHX1
Isopulegol SCHEMBL20681722 0.80 TRPA1 (0.45) CES2TRPA1TRPM8EPHX1
Isopulegol SCHEMBL8814281 0.80 TRPA1 (0.45) CES2TRPA1TRPM8EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021114021-A1 PREPARATION METHOD FOR OPTICALLY ACTIVE CITRONELLAL 万华化学集团股份有限公司 2021-06-17 WO disclosed
EP-3110810-B1 PYRAZOLE AMIDE DERIVATIVE TEIJIN PHARMA LTD (JP) 2018-05-02 EP disclosed