Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31038783 | 0.61 | KDM4E (0.32) | KDM4E | |
| SCHEMBL9265360 | 0.55 | HDAC8 (0.43) | KDM4E | |
| SCHEMBL30990996 | 0.54 | MAPT (0.38) | KDM4E | |
| SCHEMBL14085132 | 0.51 | TOP2A (0.44) | — | |
| SCHEMBL2606658 | 0.50 | KDM4E (0.51) | KDM4E | |
| SCHEMBL20125021 | 0.48 | KDM4E (0.36) | KDM4E | |
| SCHEMBL14309129 | 0.47 | HDAC8 (0.30) | — | |
| SCHEMBL11540971 | 0.47 | KDM4E (0.53) | KDM4E | |
| SCHEMBL27738467 | 0.46 | ADRA2A (0.32) | — | |
| SCHEMBL16041282 | 0.45 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180119227-A1 | NOVEL RISK BIOMARKERS FOR LUNG CANCER | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2018-05-03 | — | — | US | disclosed |