Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613027 | 0.85 | ATM (0.59) | ATMMEN1KMT2APLA2G7LMNA | |
| SCHEMBL8291064 | 0.85 | ATM (0.59) | ATMMEN1KMT2APLA2G7LMNA | |
| SCHEMBL12705075 | 0.83 | SMN1; SMN2 (0.54) | ATMMEN1KMT2APLA2G7LMNA | |
| SCHEMBL19303426 | 0.83 | SMN1; SMN2 (0.48) | ATMMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL13025225 | 0.83 | SMN1; SMN2 (0.54) | ATMMEN1KMT2APLA2G7LMNA | |
| SCHEMBL21026012 | 0.82 | ATM (0.56) | ATMMEN1KMT2APLA2G7LMNA | |
| SCHEMBL23992348 | 0.81 | SMN1; SMN2 (0.69) | ATMMEN1KMT2APLA2G7LMNA | |
| SCHEMBL19303424 | 0.81 | ATM (0.52) | ATMMEN1KMT2APLA2G7LMNA | |
| SCHEMBL22641760 | 0.79 | SMN1; SMN2 (0.45) | ATMMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL213322 | 0.76 | PLA2G7 (0.65) | MEN1KMT2APLA2G7ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459565-B1 | SAXITOXIN DERIVATIVES, METHODS AND COMPOSITIONS FOR STUDYING, IMAGING, AND TREATING PAIN | UNIV LELAND STANFORD JUNIOR (US) | 2018-05-02 | — | — | EP | disclosed |