SCHEMBL21026012

SCHEMBL21026012

NC(=O)CO/N=C/c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.56
PLA2G7 Q13093 2/20 0.54
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
LMNA P02545 5/20 0.47
SMN1; SMN2 Q16637 4/20 0.47
ALDH1A1 P00352 4/20 0.47
HTT P42858 1/20 0.47
RAB9A P51151 3/20 0.46
GALR3 O60755 1/20 0.46
NR2F2 P24468 1/20 0.46
MIF P14174 1/20 0.45
KDM4E B2RXH2 2/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
UNG P13051 1/20 0.43
NPC1 O15118 2/20 0.43
GAA P10253 1/20 0.43
TAAR1 Q96RJ0 1/20 0.43
GRIN2D O15399 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8613027 0.85 ATM (0.59) ATMPLA2G7MEN1KMT2ALMNA
SCHEMBL8291064 0.85 ATM (0.59) ATMPLA2G7MEN1KMT2ALMNA
SCHEMBL14077931 0.83 PLA2G7 (0.53) ATMPLA2G7MEN1KMT2ALMNA
SCHEMBL20104790 0.82 ATM (0.56) ATMPLA2G7MEN1KMT2ALMNA
SCHEMBL18196787 0.79 SMN1; SMN2 (0.47) ATMPLA2G7MEN1KMT2ALMNA
SCHEMBL23992348 0.78 SMN1; SMN2 (0.69) ATMPLA2G7MEN1KMT2ALMNA
SCHEMBL19303424 0.78 ATM (0.52) ATMPLA2G7MEN1KMT2ALMNA
SCHEMBL10332554 0.77 PLA2G7 (0.67) PLA2G7MEN1KMT2ALMNAALDH1A1
SCHEMBL6420965 0.75 PLA2G7 (0.69) PLA2G7MEN1KMT2ALMNAALDH1A1
SCHEMBL11143720 0.75 MAPT (0.55) MEN1KMT2ALMNASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10300156-B2 Radiotracer compositions and methods GE HEALTHCARE LIMITED (GB) 2019-05-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10300156-B2 Radiotracer compositions and methods MET, METTL14, MEN1 ATM 2648/4885PLA2G7 4345/4885MEN1 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.