Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532547 | 0.85 | DRD2 (0.39) | DRD2KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL12554693 | 0.85 | CA12 (0.45) | DRD2KMT2AALOX15RAB9ACA12 | |
| SCHEMBL20100939 | 0.84 | KMT2A (0.47) | KMT2AMAPTALOX15RAB9AALDH1A1 | |
| SCHEMBL20105088 | 0.84 | DRD2 (0.47) | DRD2KMT2AMAPTRAB9ACA12 | |
| SCHEMBL4196763 | 0.84 | DRD2 (0.39) | DRD2ALOX15TAS1R3TAS1R1THRA | |
| SCHEMBL21433742 | 0.82 | CES2 (0.38) | DRD2KMT2AMAPTALOX15TAS1R3 | |
| SCHEMBL20100951 | 0.79 | NOTUM (0.45) | KMT2AMAPTNOTUMTAS1R3TAS1R1 | |
| SCHEMBL20100937 | 0.79 | SMN1; SMN2 (0.47) | KMT2AMAPTALOX15THRBRAB9A | |
| SCHEMBL19616152 | 0.78 | DRD2 (0.45) | DRD2KMT2AMAPTTAS1R3TAS1R1 | |
| SCHEMBL12554689 | 0.78 | DRD2 (0.36) | DRD2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180116993-A1 | MODULATORS OF FARNESOID X RECEPTOR AND METHODS FOR THE USE THEREOF | XIAMEN UNIVERSITY (CN) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180116993-A1 | MODULATORS OF FARNESOID X RECEPTOR AND METHODS FOR THE USE THEREOF | NR1H4, FABP1, NR1H2 | DRD2 4763/4885MGLL 407/4885KMT2A 4075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.