Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 7/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL871832 | 0.77 | — | — | |
| SCHEMBL20614414 | 0.74 | ALDH1A1 (0.38) | BRD4KDM4EALDH1A1GLAHPGD | |
| SCHEMBL18073640 | 0.72 | BRD4 (0.35) | BRD4KDM4EALDH1A1GLAHPGD | |
| SCHEMBL29951216 | 0.71 | — | — | |
| SCHEMBL19869652 | 0.71 | BRD4 (0.42) | BRD4KDM4EALDH1A1GLAHPGD | |
| SCHEMBL20105164 | 0.71 | AURKA (0.37) | BRD4KDM4EALDH1A1GLAHPGD | |
| SCHEMBL13074741 | 0.71 | BRD4 (0.41) | BRD4KDM4EALDH1A1GLAHPGD | |
| SCHEMBL4033291 | 0.68 | GAA (0.31) | CCR1 | |
| SCHEMBL12157416 | 0.68 | BRD4 (0.35) | BRD4KDM4EALDH1A1GLAHPGD | |
| SCHEMBL4036684 | 0.68 | CCR1 (0.30) | CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3140304-B1 | BENZIMIDAZOLE DERIVATIVES | BOEHRINGER INGELHEIM INT (DE) | 2018-05-02 | — | — | EP | disclosed |