Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | REN | P00797 | 3/20 | 0.42 |
| ▸ | HTR1D | P28221 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR1E | P28566 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30600490 | 0.87 | MDM4 (0.56) | MDM4TP53CASP3 | |
| SCHEMBL17269327 | 0.87 | MDM4 (0.56) | MDM4TP53CASP3 | |
| SCHEMBL20677239 | 0.87 | MDM4 (0.56) | MDM4TP53CASP3 | |
| SCHEMBL28015870 | 0.87 | MDM4 (0.56) | MDM4TP53CASP3 | |
| SCHEMBL15164253 | 0.84 | MDM4 (0.48) | MDM4TP53CASP3HTR1DHTR2C | |
| SCHEMBL15067200 | 0.83 | MDM4 (0.46) | MDM4TP53CASP3 | |
| SCHEMBL30195106 | 0.83 | MDM4 (0.46) | MDM4TP53CASP3 | |
| SCHEMBL27890071 | 0.83 | MDM4 (0.49) | MDM4TP53CASP3HTR1DHTR2C | |
| SCHEMBL16278331 | 0.83 | MDM4 (0.46) | MDM4TP53CASP3 | |
| Trifluoroacetic Acid SCHEMBL31494720 | 0.80 | MDM4 (0.43) | MDM4TP53CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10954267-B2 | Dipeptide comprising a non-proteogenic amino acid | NOVO NORDISK A/S (DK) | 2021-03-23 | — | — | US | disclosed |
| US-20190002496-A1 | Dipeptide Comprising a Non-Proteogenic Amino Acid | NOVO NORDISK AS (DK) | 2019-01-03 | — | — | US | disclosed |
| EP-2797947-B1 | DIPEPTIDE COMPRISING A NON-PROTEOGENIC AMINO ACID | NOVO NORDISK AS (DK) | 2018-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10954267-B2 | Dipeptide comprising a non-proteogenic amino acid | DNPEP, ANPEP, NPEPPS | MDM4 431/4885TP53 181/4885CASP3 3409/4885 |
| US-20190002496-A1 | Dipeptide Comprising a Non-Proteogenic Amino Acid | DNPEP, ANPEP, NPEPPS | MDM4 431/4885TP53 181/4885CASP3 3409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.