SCHEMBL28015870

SCHEMBL28015870

O=C(N[C@@H](Cc1cnc[nH]1)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ MDM4 O15151 3/20 0.56
▸ TP53 P04637 3/20 0.56
▸ ITGB2 P05107 3/20 0.51
▸ ICAM1 P05362 3/20 0.51
▸ ITGAL P20701 3/20 0.51
▸ MME P08473 1/20 0.49
▸ ECE1 P42892 1/20 0.49
▸ MDM2 Q00987 5/20 0.49
▸ HIF1A Q16665 1/20 0.47
▸ CASP3 P42574 2/20 0.46
▸ CA1 P00915 1/20 0.46
▸ CA2 P00918 1/20 0.46
▸ AGTR2 P50052 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30600490 1.00 MDM4 (0.56) MDM4TP53ITGB2ICAM1ITGAL
SCHEMBL17269327 1.00 MDM4 (0.56) MDM4TP53ITGB2ICAM1ITGAL
SCHEMBL20677239 1.00 MDM4 (0.56) MDM4TP53ITGB2ICAM1ITGAL
SCHEMBL15164253 0.88 MDM4 (0.48) MDM4TP53MMEECE1MDM2
SCHEMBL27890071 0.88 MDM4 (0.49) MDM4TP53MMEECE1MDM2
SCHEMBL20106639 0.87 MDM4 (0.47) MDM4TP53CASP3
SCHEMBL17269328 0.82 MDM4 (0.47) MDM4TP53MDM2
SCHEMBL22444779 0.82 MDM4 (0.56) MDM4TP53MDM2CASP3
SCHEMBL27041536 0.82 MDM4 (0.56) MDM4TP53MDM2CASP3
SCHEMBL118169 0.81 MDM4 (0.59) MDM4TP53MDM2CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431505-A Freshwater fish protein antihypertensive peptide based on ethylation modification and preparation method thereof 湖北省农业科学院农产品加工与核农技术研究所 2025-02-14 — — CN claimed
CN-118047836-A Preparation method of goserelin impurity E 中肽生化有限公司 2024-05-17 — — CN claimed
CN-115611967-A Hyaluronan oligopeptide and preparation and application methods thereof 润辉生物技术(威海)有限公司 2023-01-17 — — CN claimed
CN-114939178-A Amino acid/polypeptide coordination polymer and preparation method and application thereof 中国药科大学 2022-08-26 — — CN claimed
CN-110642865-B Application of high-charge cationic porphyrin in preparation of PDT nano photosensitizer 天津大学 2021-12-07 — — CN claimed
CN-110642865-A Application of high-charge cationic porphyrin in preparation of PDT nano photosensitizer 天津大学 2020-01-03 — — CN claimed
CN-106674230-B The synthetic method of pro-his cyclic dipeptide 陕西慧康生物科技有限责任公司 2019-07-02 — — CN claimed
CN-106674230-A Synthesis method of histidine and proline cyclodipeptide 陕西慧康生物科技有限责任公司 2017-05-17 — — CN claimed
CN-101314612-B Method for solid phase polypeptide synthesis of hexarelin GL BIOCHEM SHANGHAI LTD 2011-07-20 — — CN claimed
CN-101314612-A Method for solid phase polypeptide synthesis of hexarelin GL BIOCHEM SHANGHAI LTD (CN) 2008-12-03 — — CN claimed
CN-119707960-A Preparation method of side chain Fmoc-His (Mtt) 四川鸿日医药科技有限公司 2025-03-28 — — CN disclosed
CN-119431505-A Freshwater fish protein antihypertensive peptide based on ethylation modification and preparation method thereof 湖北省农业科学院农产品加工与核农技术研究所 2025-02-14 — — CN disclosed
CN-115141255-B Pearl-derived whitening polypeptide and application thereof 欧诗漫生物股份有限公司 2024-10-22 — — CN disclosed
CN-115417914-B Hyaluronan oligopeptide and preparation and application methods thereof 润辉生物技术(威海)有限公司 2024-10-01 — — CN disclosed
CN-118290649-A RMBL resin, preparation method thereof and application thereof in polypeptide solid-phase synthesis 南京大学 2024-07-05 — — CN disclosed
CN-106674230-B The synthetic method of pro-his cyclic dipeptide 陕西慧康生物科技有限责任公司 2019-07-02 — — CN disclosed
CN-106309375-B A kind of nano particle preparations, preparation method and application 中国科学院过程工程研究所 2019-03-26 — — CN disclosed
CN-106674230-A Synthesis method of histidine and proline cyclodipeptide 陕西慧康生物科技有限责任公司 2017-05-17 — — CN disclosed
CN-106309375-A Nanoparticle preparation, and preparation method and application thereof 中国科学院过程工程研究所 2017-01-11 — — CN disclosed
CN-104610240-A Bicyclol-carnosine conjugate and preparation method and application thereof NANJING UNIVERSITY OF TECHNOLOGY 2015-05-13 — — CN disclosed
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