Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3345289 | 1.00 | KMT2A (0.38) | KMT2AMEN1MAPK1APLNRBTK | |
| SCHEMBL634842 | 1.00 | KMT2A (0.38) | KMT2AMEN1MAPK1APLNRBTK | |
| SCHEMBL22380465 | 0.87 | MEN1 (0.38) | KMT2AMEN1MAPK1APLNRBTK | |
| SCHEMBL22380661 | 0.87 | MEN1 (0.38) | KMT2AMEN1MAPK1APLNRBTK | |
| SCHEMBL635108 | 0.87 | MEN1 (0.38) | KMT2AMEN1MAPK1APLNRBTK | |
| SCHEMBL9666907 | 0.86 | KMT2A (0.39) | KMT2AMEN1MAPK1APLNRBTK | |
| SCHEMBL19558543 | 0.82 | APLNR (0.37) | KMT2AMEN1MAPK1APLNRHDAC4 | |
| SCHEMBL13748923 | 0.82 | APLNR (0.37) | KMT2AMEN1MAPK1APLNRHDAC4 | |
| SCHEMBL19174581 | 0.80 | APLNR (0.35) | KMT2AMEN1MAPK1APLNRHDAC4 | |
| SCHEMBL27872243 | 0.79 | MEN1 (0.43) | KMT2AMEN1MAPK1APLNRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10442792-B2 | Synthetic route to anti-viral agents | ABBVIE INC. (US) | 2019-10-15 | — | — | US | disclosed |
| US-20190084966-A1 | SYNTHETIC ROUTE TO ANTI-VIRAL AGENTS | ABBVIE INC. | 2019-03-21 | — | — | US | disclosed |
| EP-3315497-A1 | METHOD FOR PRODUCING FLUORINE-CONTAINING CYCLOPROPANE CARBOXYLIC ACID COMPOUND | Central Glass Co., Ltd. (JP) | 2018-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10442792-B2 | Synthetic route to anti-viral agents | ACE, ACE2, PREP | KMT2A 2623/4885MEN1 3202/4885MAPK1 2037/4885 |
| US-20190084966-A1 | SYNTHETIC ROUTE TO ANTI-VIRAL AGENTS | ACE, ACE2, PREP | KMT2A 2623/4885MEN1 3202/4885MAPK1 2037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.