Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.33 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21732711 | 0.97 | CYP3A4 (0.42) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| SCHEMBL25670420 | 0.91 | CYP3A4 (0.42) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| SCHEMBL21732700 | 0.88 | CYP3A4 (0.44) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| SCHEMBL21732899 | 0.88 | CYP3A4 (0.40) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| SCHEMBL21732694 | 0.85 | CYP3A4 (0.41) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| SCHEMBL21732707 | 0.84 | ALOX15 (0.32) | CYP3A4TSHRTDP1L3MBTL1ENPP2 | |
| SCHEMBL18193206 | 0.82 | CYP3A4 (0.43) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| SCHEMBL25670454 | 0.82 | CYP3A4 (0.49) | CYP3A4TSHRTDP1ATML3MBTL1 | |
| SCHEMBL21732699 | 0.81 | ALOX15 (0.31) | CYP3A4TSHRTDP1ALDH1A1 | |
| SCHEMBL20107506 | 0.80 | CYP3A4 (0.38) | CYP3A4TSHRTDP1ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667866-B2 | Phosphorous containing compounds and uses thereof | AFTON CHEMICAL CORPORATION (US) | 2023-06-06 | — | — | US | disclosed |
| US-11066619-B2 | Phosphorous containing compounds and uses thereof | AFTON CHEMICAL CORPORATION (US) | 2021-07-20 | — | — | US | disclosed |
| US-20200056114-A1 | Phosphorous Containing Compounds and Uses Thereof | AFTON CHEMICAL CORP (US) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200056114-A1 | Phosphorous Containing Compounds and Uses Thereof | SOST, PHOSPHO1, PSPH | CYP3A4 4745/4885TSHR 4882/4885TDP1 701/4885 |
| US-11667866-B2 | Phosphorous containing compounds and uses thereof | SOST, PHOSPHO1, PSPH | CYP3A4 4745/4885TSHR 4882/4885TDP1 701/4885 |
| US-11066619-B2 | Phosphorous containing compounds and uses thereof | SOST, PHOSPHO1, PSPH | CYP3A4 4745/4885TSHR 4882/4885TDP1 701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.