Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20108101 | 0.82 | DHODH (0.62) | DHODH | |
| SCHEMBL29816309 | 0.82 | DHODH (0.62) | DHODH | |
| SCHEMBL20107685 | 0.82 | DHODH (0.51) | TLR7DHODH | |
| SCHEMBL20107915 | 0.82 | TLR7 (0.49) | TLR7DHODH | |
| SCHEMBL28953475 | 0.78 | DHODH (0.44) | DHODH | |
| SCHEMBL20107888 | 0.77 | DHODH (0.47) | TLR7DHODH | |
| SCHEMBL21471173 | 0.77 | DHODH (0.50) | TLR7DHODH | |
| SCHEMBL20107976 | 0.76 | KDM4E (0.38) | — | |
| SCHEMBL24282505 | 0.76 | DHODH (0.77) | DHODH | |
| SCHEMBL20107795 | 0.75 | DHODH (0.80) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3532468-B1 | 2,4,5-TRISUBSTITUTED 1,2,4-TRIAZOLONES USEFUL AS INHIBITORS OF DHODH | BAYER AG (DE) | 2022-03-23 | — | — | EP | disclosed |
| WO-2018077923-A1 | 2,4,5-TRISUBSTITUTED 1,2,4-TRIAZOLONES USEFUL AS INHIBITORS OF DHODH | BAYER AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | WO | disclosed |