Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | SPNS2 | Q8IVW8 | 2/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934071 | 0.85 | RARB (0.52) | HTR2ARARB | |
| SCHEMBL26313621 | 0.78 | CYP1A2 (0.61) | HRH1HTR2AMAOACYP1A2CYP2A6 | |
| SCHEMBL8501852 | 0.78 | TAAR1 (0.67) | HRH1HTR2AMAOACYP1A2CYP2A6 | |
| SCHEMBL8498343 | 0.78 | TAAR1 (0.67) | HRH1HTR2AMAOACYP1A2CYP2A6 | |
| SCHEMBL8501738 | 0.78 | TAAR1 (0.67) | HRH1HTR2AMAOACYP1A2CYP2A6 | |
| SCHEMBL8501179 | 0.78 | TAAR1 (0.67) | HRH1HTR2AMAOACYP1A2CYP2A6 | |
| SCHEMBL8502039 | 0.78 | TAAR1 (0.67) | HRH1HTR2AMAOACYP1A2CYP2A6 | |
| SCHEMBL8500424 | 0.78 | TAAR1 (0.67) | HRH1HTR2AMAOACYP1A2CYP2A6 | |
| SCHEMBL8502202 | 0.78 | TAAR1 (0.67) | HRH1HTR2AMAOACYP1A2CYP2A6 | |
| SCHEMBL4867215 | 0.78 | TAAR1 (0.67) | HRH1HTR2AMAOACYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964635-B1 | ANTIVIRAL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2018-05-02 | — | — | EP | disclosed |