Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | IGF1R | P08069 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 3/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | AKT2 | P31751 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5609503 | 0.94 | TAAR1 (0.70) | CYP1A2CYP2A6TAAR1MAOAIGF1R | |
| SCHEMBL8501738 | 0.91 | TAAR1 (0.67) | CYP1A2CYP2A6TAAR1MAOAIGF1R | |
| SCHEMBL8502202 | 0.91 | TAAR1 (0.67) | CYP1A2CYP2A6TAAR1MAOAIGF1R | |
| SCHEMBL8501852 | 0.91 | TAAR1 (0.67) | CYP1A2CYP2A6TAAR1MAOAIGF1R | |
| SCHEMBL4867215 | 0.91 | TAAR1 (0.67) | CYP1A2CYP2A6TAAR1MAOAIGF1R | |
| SCHEMBL8502039 | 0.91 | TAAR1 (0.67) | CYP1A2CYP2A6TAAR1MAOAIGF1R | |
| SCHEMBL8498343 | 0.91 | TAAR1 (0.67) | CYP1A2CYP2A6TAAR1MAOAIGF1R | |
| SCHEMBL8500424 | 0.91 | TAAR1 (0.67) | CYP1A2CYP2A6TAAR1MAOAIGF1R | |
| SCHEMBL8501179 | 0.91 | TAAR1 (0.67) | CYP1A2CYP2A6TAAR1MAOAIGF1R | |
| Hydrochloric Acid SCHEMBL17260636 | 0.91 | TAAR1 (0.67) | CYP1A2CYP2A6TAAR1MAOAIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257357-A1 | PROBENECID COMPOUNDS FOR THE TREATMENT OF INFLAMMASOME-MEDIATED LUNG DISEASE | BACAINN BIOTHERAPEUTICS, LTD. (KY) | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257357-A1 | PROBENECID COMPOUNDS FOR THE TREATMENT OF INFLAMMASOME-MEDIATED LUNG DISEASE | NLRP3, PYCARD, NLRP1 | CYP1A2 1919/4885CYP2A6 3986/4885TAAR1 3573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.