Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.69 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.69 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.69 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.69 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.69 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.69 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.69 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.69 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.69 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11694913 | 0.94 | HDAC8 (0.75) | ALDH1A1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL2183716 | 0.90 | ALDH1A1 (0.76) | ALDH1A1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL11660177 | 0.88 | ALDH1A1 (0.73) | ALDH1A1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL9479632 | 0.87 | MAPT (0.81) | ALDH1A1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL24474005 | 0.86 | HPGD (0.80) | ALDH1A1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL16013604 | 0.85 | TP53 (0.67) | ALDH1A1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL19069947 | 0.85 | TP53 (0.67) | ALDH1A1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL14424290 | 0.85 | HDAC8 (0.63) | ALDH1A1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL1897242 | 0.84 | SOAT2 (0.79) | ALDH1A1HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL282938 | 0.83 | SOAT2 (0.82) | ALDH1A1HDAC1HDAC2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964635-B1 | ANTIVIRAL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2018-05-02 | — | — | EP | disclosed |