Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 12/20 | 0.52 |
| ▸ | LIPG | Q9Y5X9 | 12/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | F11 | P03951 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2590038 | 1.00 | LPL (0.52) | LPLLIPGESR2CA1CA2 | |
| SCHEMBL19110515 | 1.00 | LPL (0.52) | LPLLIPGESR2CA1CA2 | |
| Hydrochloric Acid SCHEMBL15137435 | 0.98 | LPL (0.50) | LPLLIPGESR2CA1CA2 | |
| Hydrochloric Acid SCHEMBL26988609 | 0.98 | LPL (0.50) | LPLLIPGESR2CA1CA2 | |
| SCHEMBL87138 | 0.84 | LIPG (0.55) | LPLLIPGESR2CA1CA2 | |
| SCHEMBL28371250 | 0.82 | LIPG (0.57) | LPLLIPGESR2CA1CA2 | |
| SCHEMBL228212 | 0.81 | LPL (0.71) | LPLLIPGESR2CA1CA2 | |
| SCHEMBL24775237 | 0.81 | LIPG (0.52) | LPLLIPGESR2CA1CA2 | |
| SCHEMBL24774874 | 0.81 | LIPG (0.52) | LPLLIPGESR2CA1CA2 | |
| SCHEMBL14694622 | 0.81 | LIPG (0.52) | LPLLIPGESR2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964635-B1 | ANTIVIRAL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2018-05-02 | — | — | EP | disclosed |