Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25646278 | 0.82 | — | — | |
| SCHEMBL18738003 | 0.81 | PPARG (0.38) | — | |
| SCHEMBL21185094 | 0.80 | PPARA (0.41) | MAPTKDM4E | |
| SCHEMBL20108615 | 0.80 | ABAT (0.36) | SMN1; SMN2KDM4E | |
| SCHEMBL8283344 | 0.80 | TRPA1 (0.30) | — | |
| SCHEMBL12068088 | 0.77 | — | — | |
| SCHEMBL18636296 | 0.76 | — | — | |
| SCHEMBL12810760 | 0.76 | RXRA (0.42) | LMNAKDM4EMEN1KMT2A | |
| SCHEMBL8281890 | 0.75 | ESR1 (0.37) | MAPTLMNANPC1RAB9AKDM4E | |
| SCHEMBL14038082 | 0.75 | TSHR (0.33) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964635-B1 | ANTIVIRAL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2018-05-02 | — | — | EP | disclosed |