Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PDE5A | O76074 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20108810 | 0.79 | KMT2A (0.67) | KMT2ANPSR1MEN1HTTLMNA | |
| SCHEMBL293214 | 0.67 | HTR3E (0.48) | KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL20109380 | 0.67 | KMT2A (0.62) | KMT2ANPSR1MEN1HTTLMNA | |
| SCHEMBL21239325 | 0.64 | KMT2A (0.58) | KMT2ANPSR1MEN1HTTLMNA | |
| SCHEMBL14544921 | 0.64 | CKS1B (0.47) | — | |
| SCHEMBL20109613 | 0.62 | SMO (0.57) | KMT2ANPSR1MEN1HTTLMNA | |
| SCHEMBL17678343 | 0.62 | GAA (0.42) | MAPTALDH1A1HPGD | |
| SCHEMBL10811062 | 0.62 | MAPT (0.48) | KMT2ANPSR1MEN1HTTLMNA | |
| SCHEMBL20108970 | 0.62 | HRH4 (0.38) | KMT2ASMO | |
| SCHEMBL24681521 | 0.62 | NOTUM (0.51) | KMT2AMEN1HTTLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018080216-A1 | PHENYL PHTHALAZINE DERIVATIVE, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2018-05-03 | — | — | WO | disclosed |